La disponibilidad de glucógeno muscular es un limitante del rendimiento en el ejercicio físico, en especial el de resistencia. Varios estudios han demostrado que la ingesta durante 5 días de 5 g de creatina (Cr) más hidratos de carbono (CHO) aumentan los depósitos de glucógeno muscular post-ejercicio comparado con la ingesta de CHO únicamente.


Hace ya tiempo se publicó los resultados de un estudio . 2016 US National Library of Medicine cuyo objetivo fue ratificar los hallazgos comentados, a la vez que identificar las posibles causas de esa ayuda o mejora en la reposición del sustrato.


Los sujetos voluntarios pedalearon hasta el agotamiento a una intensidad correspondiente al 70% VO2max. Se obtuvieron muestras musculares por biopsia en reposo, inmediatamente después del ejercicio, y 1, 3 y 6 días post-ejercicio, en dos condiciones: con y sin suplementación con 20 g de Cr/día, con una dieta rica en CHO (37,5 kcal/kg/día; >80% calorías totales).


Los resultados mostraron que el ejercicio disminuyó el glucógeno muscular en la misma cuantía en ambos grupos. La suplementación con Cr aumentó los depósitos de glucógeno muscular por encima del grupo placebo, 1 día después de iniciar la suplementación, manteniéndose posteriormente. Los autores confirmaron que la suplementación con Cr +`dieta rica en CHO aumenta los depósitos de glucógeno muscular a las 24 h, aun cuando el contenido de Cr muscular solo aumentó un 10% en el músculo.




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